Disease: Rectal Carcinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC3 O43542 X-ray repair cross complementing 3 1.9E-10 0.505 0.769
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
MUTYH Q9UIF7 mutY DNA glycosylase Enzyme 1.3E-18 0.521 0.769
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
MSR1 P21757 macrophage scavenger receptor 1 Enzyme 2.2E-20 0.553 0.654
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MIR21 microRNA 21 0.363 0.846
MIR17HG Q75NE6 miR-17-92a-1 cluster host gene 0.483 0.808